Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds
نویسندگان
چکیده
منابع مشابه
Producing Gelatin Nanoparticles as Delivery System for Bovine Serum Albumin
Background: Progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. Delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. Methods: In this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (GNP) as a d...
متن کاملThermodynamic Analysis for Cationic Surfactants Binding to Bovine Serum Albumin
In the present study, the binding isotherms for interaction of a homologous series of n-alkyltrimethyl ammonium bromides with bovine serum albumin (BSA) have been analyzed on basis of intrinsic thermodynamic quantities. In this regards, the intrinsic Gibbs free energy of binding, AGb(i,)„ has been estimated at various surfactant concentrations and its trend of variation for both binding sets ha...
متن کاملInteraction of Phthalocyanine with Egg albumin and Bovine serum albumin
The interaction of bovine serum albumin ( BSA) and egg albumin with water solublephthalocyanine, cobalt (ΙΙ) 4, 4′ , 4′′, 4′′′- tetrasulfophthalocyanine ( CoTSPc) , has been studiedby the UV- Vis method at pH 7.0 and five different temperatures 20, 25, 30, 35 and 40°C. Theformation constants have been elucidated by using spectrophotometric titration and computerSQUAD program data refinement. Th...
متن کاملBovine Serum Albumin–dye Binding
The interaction of the dye reactive bright red 6C with bovine serum albumin has been investigated. Formation of a complex between reactive bright red 6C and bovine serum albumin was detected by use of absorption difference spectroscopy. The curves obtained by titration of the protein against the dye were recorded at different pH and ionic strength of the solution. An unusual form of titration c...
متن کاملSerum Antibody to Bovine Serum Albumin I
To evaluate the re lat ionship be tween tumor burden and c i rculat ing immune complexes (IC) in ch i ldren with neurob lastoma (NBL), we studied sera col lected at intervals from pat ients with d isseminated (Stage III or IV) NBL. Sera from 10 of 12 pat ients conta ined IC by the Raji cell assay at some time dur ing the first 9 to 11 months of the study. H igher IC levels were observed in sera...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2003
ISSN: 0022-202X
DOI: 10.1046/j.1523-1747.2003.12083.x